2-(2-HYDROXY-1-NAPHTHYL)ACETIC ACID

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 1450, 1960 DOI: 10.1021/ja01491a043

Purification Methods

Crystallise the acid from EtOH/water (1:9, v/v, activated charcoal), H2O (m 157o) or xylene (m 147o). Dry it under vacuum, over silica gel, in the dark. Store it in the dark at -20o [Gafni et al. J Phys Chem 80 898 1976]. It forms a cyclic lactone (m 107o) readily. [Beilstein 10 II 218, 10 III 1102, 10 IV 1201.]