Description
The sodium salt of N-hydroxy-2-pyridinethiones has a
germicidal activity againts yeasts and fungi. Sodium
omadine is a 40% aqueous solution of sodium
pyrithione.
Uses
It is used in the metallurgical industry as
a component of water-based metalwork fluids, of
aceto-polyvinyl lattices, water-based printer's ink,
lubrieant for synthetie fibers and anti-dandruff shampoos.
A case was reported in a metallurgie worker.
Definition
ChEBI: A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn2+ ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 4362, 1950
DOI: 10.1021/ja01166a008
