Setrusumab
- Product NameSetrusumab
- CAS1847394-95-9
- CBNumberCB88080989
- MW0
- MOL FileMol file
- MSDS FileSDS
Setrusumab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0624049 | 1mg | $433 | Setrusumab 99.9% |
Buy |
| ChemScene CS-0624049 | 5mg | $1300 | Setrusumab 99.9% |
Buy |
| ChemScene CS-0624049 | 10mg | $2058 | Setrusumab 99.9% |
Buy |
| aablocks AA02EO84 | 1mg | $664 | Setrusumab ≥95%(SDS-PAGE&SEC-HPLC) |
Buy |
| aablocks AA02EO84 | 5mg | $2000 | Setrusumab ≥95%(SDS-PAGE&SEC-HPLC) |
Buy |
Setrusumab Chemical Properties,Usage,Production
Uses
Setrusumab (BPS 804) is a fully human monoclonal antibody targets sclerostin. Setrusumab efftively improves bone strength. Setrusumab can be used for the resesrch of Osteogenesis Imperfecta (OI) and cancer[1].in vivo
Setrusumab (100 mg/kg; i.v. once a week for 4 weeks) inhibits breast cancer-induced bone metastases and muscle weakness in mice[1].
| Animal Model: | 8-week-old female immune-compromised CB-17/lcr-Prkdcscid/Rj mice with MDA-MB-231 breast cancer cells injection[1] |
| Dosage: | 100 mg/kg |
| Administration: | Intravenous injection; 100 mg/kg once a week for 4 weeks |
| Result: | Significantly inhibited tumor growth in bones and breast cancer cell dissemination into other organs. Inhibited breast cancer-induced osteolytic lesions and subsequent loss of bone mass of the distal femur and of the proximal tibia. Redued phosphorylation of IKKα, IKKβ, and p65. |
References
[1] Hesse E, et al. Sclerostin inhibition alleviates breast cancer-induced bone metastases and muscle weakness. JCI Insight. 2019 Apr 9;5(9):e125543.Preparation Products And Raw materials
Setrusumab Suppliers
Global(17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 18916372613 | yanzihan@shyuanye.com | China | 87240 | 60 | |
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 7996 | 62 | |
| 15817493340 | 981810490@qq.com | China | 1577 | 58 | |
| 027-65317797 15926423062 |
422450190@qq.com | China | 10302 | 58 | |
| 027-65279366 18108604356 |
products@biolabreagent.com | China | 9864 | 58 | |
| 13720134139 086-15871494362 13720134139 |
orders@jknbiochem.com | China | 7284 | 58 | |
| 021-65675885 18964387627 |
customer_service@efebio.com | China | 11963 | 58 | |
| 027-027-16602739303 16602739303 |
673003916@qq.com | China | 4622 | 58 | |
| 15111215862 18229892877 |
3062105966@qq.com | China | 5571 | 58 | |
| 17316404525 17316404525 |
209533805@qq.com | China | 9772 | 58 |
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