Chemical Properties
light pink to beige or light brownish. 2-Amino-1-propene-1,1,3-tricarbonitrile [868-54-2], 2-amino-1,1,3-tricyanopropene, malononitrile dimer, (NC)2C=C (NH2) CH2CN, Mr 132.13, mp 171 – 173℃, is a light brownish powder, insoluble in water.
Uses
2-Amino-1,1,3-propenetricarbonitrile stimulates choline acetyltransferase activity in animals. A neurotrophic agent with potential therapeutic effect on cholinergic disorders.
Biochem/physiol Actions
2-Amino-1,1,3-propenetricarbonitrile is a key intermediate in synthesis of various heterocyclic compounds. 2-Amino-1,1-3-tricyanopropene undergoes condensation reaction with aromatic nitroso compounds to form useful coloring agents. 2-Amino-1,1-3-tricyanopropene reacts with 1,3-dithiole-derived polyenals to form push–pull systems with (Z)-geometry around the newly formed carbon-carbon double bond.
Synthesis
Malononitrile dimer is obtained from the base-catalyzed dimerization of malononitrile. It has been investigated as a potential precursor for new dyes but it has no current industrial significance.
