Uses
Sorbitol dehydrogenase is an oxidoreductase. Sorbitol dehydrogenase can be used as a marker for drug-induced liver injury[1].
Description
SORD Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (1-357a.a.) and having a molecular mass of 38.3kDa.
SORD is purified by proprietary chromatographic techniques.
Background
SORD, also referred to as sorbitol dehydrogenase, belongs to the zinc-containing alcohol dehydrogenase family. It is widely produced. The lens of the eyeand the kidney are the protein highest production areas. Zinc-dependent interconversion of polyols, like sorbitol and xylitol, are enzymatically catalysed to their respective ketoses by SORD.
References
[1] Bekhit M, et al. Determination of sorbitol dehydrogenase in microsamples of human serum. Talanta. 2021 Dec 1;235:122730. DOI:
10.1016/j.talanta.2021.122730
