Description
Pyrrolidino PAF C-
16 is a synthetic analog of PAF C-
16. It is a potent mediator of PAF-
like activities, including hypotension and platelet aggregation, where it is approximately 3-
10 times more potent than PAF itself.
Uses
Pyrrolidino PAF C-16 is a platelet activating factor ( PAF ) analogue that has hypohematic effects[1].
Definition
ChEBI: Pyrrolidinium, 1-[(7r)-7-(acetyloxy)-4-hydroxy-4-oxido-3,5,9-trioxa-4-phosphapentacos-1-yl]-1-methyl-, inner salt is a glycerophospholipid.
References
[1]. shigenobu k, masuda y, tanaka y, et al. platelet activating factor analogues: lack of correlation between their activities to produce hypotension and endothelium-mediated vasodilation. j pharmacobiodyn. 1985 feb;8(2):128-33.
[2]. kasuya y, masuda y, shigenobu k. hypotensive actions of some analogues of platelet-activating factor (paf) with higher potencies than natural paf. can j physiol pharmacol. 1984 apr;62(4):457-9.
