ChemicalBook CAS DataBase List 6-HYDROXYFLAVONE

6-HYDROXYFLAVONE

Chemical Properties

Melting point	234-236 °C (lit.)
Boiling point	320.83°C (rough estimate)
Density	1.2653 (rough estimate)
refractive index	1.5740 (estimate)
pka	8.98±0.40(Predicted)
form	powder to crystal
color	Light yellow to Yellow to Green
BRN	15827
InChI	1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H
InChIKey	GPZYYYGYCRFPBU-UHFFFAOYSA-N
SMILES	Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3
LogP	4.445 (est)
CAS DataBase Reference	6665-83-4(CAS DataBase Reference)
FDA UNII	148S6Z78H6
UNSPSC Code	12352100
NACRES	NA.22

Symbol(GHS)

Signal word

Warning

Hazard statements

H335-H315-H319

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

Hazard Note

Irritant

HS Code

2932.99.7000

Storage Class

11 - Combustible Solids

NFPA 704:

Product number	Packaging	Price	Product description	Buy
Sigma-Aldrich 411035	1g	$63.46	6-Hydroxyflavone 98%	Buy
TCI Chemical H0851	1g	$48	6-Hydroxyflavone >98.0%(T)(HPLC)	Buy
TCI Chemical H0851	5g	$116	6-Hydroxyflavone >98.0%(T)(HPLC)	Buy
TRC H942413	1g	$175	6-Hydroxyflavone	Buy
AK Scientific Y2019	10g	$198	6-Hydroxyflavone	Buy

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3751	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32470	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
GLR Innovations	+91 9891111994	info@glrgroup.in	India	4535	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39042	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49964	58

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Animal Model:	Male ICR mice (20-36 g)^[4]
Dosage:	6, 12, 25, 50 and 100 mg/kg
Administration:	Oral administration (p.o.); Single dose; 45 minutes before test
Result:	Showed anti-anxiety effects on behavioral tests.

Animal Model:	Cisplatin (HY-17394) treated male Sprague-Dawley rats (200-250 g)^[5]
Dosage:	25 and 50 mg/kg
Administration:	Intraperitoneal injection (i.p.); 15 days
Result:	Significantly attenuated the Cisplatin associated detrimental changes in the body weight, and serum levels of creatinine and urea at both 25 mg/kg and 50 mg/kg. Preserved the renal histoarchitecture from the toxicological influence of Cisplatin. Reduced the Cisplatin-induced lipid peroxidation and corrected the renal antioxidant status.