Benzyl-PEG6-azide
- Product NameBenzyl-PEG6-azide
- CAS86770-73-2
- CBNumberCB83048690
- MFC19H31N3O6
- MW397.47
- MDL NumberMFCD29049387
- MOL File86770-73-2.mol
- MSDS FileSDS
Benzyl-PEG6-azide Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| aablocks AA01FVG4 | 100mg | $362 | 19-Azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane 95% |
Buy |
| aablocks AA01FVG4 | 250mg | $465 | 19-Azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane 95% |
Buy |
| aablocks AA01FVG4 | 1g | $1184 | 19-Azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane 95% |
Buy |
| ACHEMBLOCK Y232011 | 250MG | $470 | 19-Azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane 95% |
Buy |
| ACHEMBLOCK Y232011 | 1G | $1250 | 19-Azido-1-phenyl-2,5,8,11,14,17-hexaoxanonadecane 95% |
Buy |
Benzyl-PEG6-azide Chemical Properties,Usage,Production
Uses
Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Benzyl-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.Biological Activity
Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].IC 50
PEGsReferences
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Preparation Products And Raw materials
Benzyl-PEG6-azide Suppliers
Global(26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 027-65563561 | sales@borenpharm.com | China | 1245 | 55 | |
| 0371-0371-55629727 13323845623 |
2885676761@qq.com | China | 9956 | 58 | |
| 0512-56316828 400-867-5858;400-867-5858 |
info@amateksci.com | China | 28760 | 58 | |
| 021-61469567 13774476675 |
sales@fdc-chemical.com | China | 10000 | 58 | |
| +86-156-80926068 +86-15680926068 |
1924344760@qq.com | China | 4229 | 58 | |
| 0371-55051623 18137891487 |
3983243027@qq.com | China | 9987 | 58 | |
| +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19904 | 58 | |
| 027-65563561 18717150066 |
3207347307@qq.com | CHINA | 1238 | 58 | |
| 15921040873 | 1434142450@qq.com | CHINA | 7643 | 58 | |
| 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
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