Description
(–)-β-Pinene is a bicyclic monoterpene that has been found in various plants, including
C. sativa, with diverse biological activities. It is lethal to
S. littoralis third instar larvae (LD
50 = 65 μg/larva). (–)-β-Pinene inhibits infectious bronchitis virus (IBV) replication (IC
50 = 1.32 mM) and exhibits a cytotoxic concentration (CC
50) value of greater than 10 mM in Vero cells.
In vivo, (–)-β-pinene (100 mg/kg) decreases immobility time in the forced swim test in mice, an effect that can be reversed by the serotonin (5-HT) receptor subtype 5-HT
1A antagonist WAY-100635 .
Uses
(-)-β-Pinene has been used as a standard for the analysis of terpenoid compounds in plant essential oils by GC analysis. It may be used as a building block to synthesize natural products such as grandisol, robustadial and (+)-nopinone. (-)-β-Pinene undergoes hydroformylation in the presence of platinum/tin catalysts to form
trans-10-formylpinane.
Uses
It is a useful biochemical for proteomics research. It is also employed in the preparation of natural products, such as grandisol and robustadial. It is also applied as perfuming agent in cosmetics industry.
