Chemical Properties
colorless to yellow viscous liquid
Uses
1-(Tetrahydro-2-furoyl)-piperazine (Terazosin EP Impurity N) has been used as a reactant for the preparation of pyrazol-3-propanoic acid derivatives as inhibitors of leukotriene biosynthesis in human neutrophils.
Definition
ChEBI: 1-(Tetrahydro-2-furoyl)piperazine is a member of phytanoyl-CoAs.
Synthesis
1-(Tetrahydro-2-furoyl)piperazine was prepared by using tetrahydrofurfuryl alcohol as the starting material, and the target compound tetrahydrofurfuryl piperazine was prepared by oxidizing tetrahydrofurfuryl acid, chlorinating to prepare acyl chloride and then acylating with piperazine.