Uses
Glycophorin A was used to study the
Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction.
Uses
Glycophorin A (GpA) is used as a model system for extensive experimental, theoretical, and simulation studies focusing on TM protein association. Glycophorin A is used to study the mechanism of kinase activation in the receptor for colony-stimulating factor 1. It is used to analyse glycoproteins separated by two-dimensional gel electrophoresis.
General Description
Glycophorin A cconsists of a glycosylated extracellular domain, a single transmembrane α-helix and a cytoplasmic COOH-terminal domain.
Biochem/physiol Actions
Glycophorin (GYPA) is involved in the mode of entry of the Plasmodium falciparum parasite into erythrocytes. It is also implicated in intraplaque hemorrhage as well as in the macrophage infiltration in coronary atheromas.
