Description
This amorphous pyrrolizidine alkaloid has been isolated from Arnsinckia hispida
(Ruiz et Pav.) Johnst., A. interrnedia Fisch & Mey, and A. lycopsoides Lehm. It
is dextrorotatory having [α]
20D + 3.1 ° (c 5.98, EtOH). Alkaline hydrolysis yields
retronecine and viridifloric acid.
Uses
(+)-Lycopsamine, occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens.It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.
Definition
ChEBI: Lycopsamine is a member of pyrrolizines.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
References
Cu1venor, Smith., Austral. 1. Chern., 19, 1955 (1966)
