SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE

Chemical Properties

White solid

Uses

Sp-cAMPS is an activator of phosphotransferase and cAMP-dependent kinase.

Biochem/physiol Actions

Sp-Diastereomer of adenosine 3′,5′-cyclic monophosphorothioate is a potent, membrane-permeable activator of cAMP dependent protein kinase I and II that mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases; exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP.

storage

Store at -20°C