Uses
4-[6-(3,6-Diazabicyclo[3.1.1]hept-3-yl)-3-pyridinyl]-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile Dihydrochloride may be useful in the preparation of heteroaryl-substituted pyrazolo[1,5-a]pyridines as RET inhibitors.
Application
4-(6-(3,6-Diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile dihydrochloride is an intermediate of Selpercatinib which is a highly selective, potent RET inhibitor, an oral drug used to treat cancers in people.
![4-(6-(3,6-Diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile dihydrochloride Structure](https://www.chemicalbook.com/CAS/20211123/GIF/2222752-06-7.gif)
