Physical properties
clear light yellow liquid, bp 40–42 °C/0.15 Torr,
53–54 °C/0.6 mmHg; d = 1.16 g mL?1 at 20 °C; n20
D 1.405.
Uses
Silylation reagent used to introduce the dimethylthexylsilyl
(TDS) group; complexation reagent to activate electrophiles.
Dimethylthexylsilyl trifluoromethanesulfonate
(TDSOTf) is generally used as a bulky silylation reagent.
Preparation
Dimethylthexylsilyl chloride and trifluoromethanesulfonic acid are heated to 60°Cfor 4–5 h and the
resulting silyl ester is isolated by distillation.
