ANB-NOS

Description

ANB-NOS Crosslinker contains a nitrophenyl azide group and an amine reactive NHS ester group. It is also able to react with nucleophiles.

Uses

Anb-Nos Crosslinker can be used for devices implanted in the eyes to treat glaucoma and/or dry eye.

Uses

Photoactive, heterobifunctional cross-linking reagent. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. Second bonding occurs during UV irradiation (250-350 nm) via reactive nitrene. The latter bonding is rapid and non-specific.