Description
5-
cis Iloprost is the C-
5
cis-
isomer of iloprost, a second generation structural analog of prostaglandin I
2 (prostacyclin). Iloprost displays ten-
fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.
1 There are no published studies of the pharmacological properties of 5-
cis iloprost.
References
1. Schr?r, K., Darius, H., Matzky, R., et al.
The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) — equipotent to PGI2 in vitro Naunyn Schmiedebergs Arch. Pharmacol. 316(3),252-255(1981).
