82889-99-4

5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I₂ (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.¹ There are no published studies of the pharmacological properties of 5-cis iloprost.

1. Schr?r, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) — equipotent to PGI₂ in vitro Naunyn Schmiedebergs Arch. Pharmacol. 316(3),252-255(1981).