Description
Cy3 amine is a functionalized cyanine dye containing a free amine group, which can be conjugated with reactive groups such as NHS esters, carboxy groups, epoxides, etc.
Chemical Properties
Appearance: Red solid
ex/em: 554/566 nm (PBS buffer)
Extinction coefficient (ε): 150000 Lmol1cm1
Quantum yield (Φ): 0.31
Uses
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm)[1].
References
[1] Zhang C, et, al. Influence of size, crosslinking degree and surface structure of poly(N-vinylcaprolactam)-based microgels on their penetration into multicellular tumor spheroids. Biomater Sci. 2019 Nov 1;7(11):4738-4747. DOI:
10.1039/c9bm01132c
Fluoresene quantum yield
0.31
Extinction Coefficient
150000