Anti-Golgi phosphoprotein 2

Uses

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

General Description

GOLM1 (Golgi membrane protein 1) is a resident, type II, 73kDa, Golgi-localized integral membrane protein consisting of an N-terminal transmembrane domain and a coiled-coil domain at the C-terminal luminal surface of the Golgi apparatus. It is expressed in the biliary epithelial cells of normal human tissues and sera of liver disease patients.

Biochem/physiol Actions

Golgi membrane protein 1 (GOLM1) is overexpressed in human lung adenocarcinoma and hepatocellular carcinoma. GOLM1 expression is also upregulated in tissue and urine samples of prostate cancer patients. Thus, this protein can be used as a potential biomarker of prostate cancer.