Chemical Properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses
The 2,2,2-Trichloroethyl (TCE) moiety of 2,2,2-trichloroethanol is mainly used as a protecting group for acids, acetals and also phosphoryl groups of nucleotides. It can be easily cleaved by zinc reduction.
Some of its other application include:
- Conversion of per-O-acetylated sugars to per-O-acetylated trichloroethyl derivatives.
- Preparation of TCE ester of chlorosulfuric acid.
- Preparation of 2,2,2-trichloroethyl acetimidate hydrochloride.
Uses
Intermediate, anesthetic.
Uses
2,2,2-Trichloroethanol (TCE) is an active metabolite of Trichloroacetaldehyde monohydrate [chloral hydrate (CH)] (T774055), a sedative/hypnotic that increases cerebral blood flow (CBF).
Definition
ChEBI: 2,2,2-trichloroethanol is a chloroethanol. It has a role as a mouse metabolite.
Safety Profile
Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion andrectal routes. Human mutation data reported. Explosivereaction with concentrated sodium hydroxide solutions.When heated to decomposition it emits toxic fumes ofClí. Us
IC 50
Human Endogenous Metabolite
