Uses
Cyanofenphos is an agricultural pesticide used in the protection against insects and fungal diseases.
Definition
ChEBI: Cyanofenphos is a nitrile and a member of benzenes.
Production Methods
The production of cyanofenphos typically involves a multi-step synthesis starting with the preparation of phenylphosphonothioic acid derivatives. These intermediates are then reacted with 4-cyanophenol and ethanol under controlled conditions to form the ester linkages characteristic of cyanofenphos. The process includes thionation, where a sulphur atom is introduced to the phosphorus centre, followed by esterification to attach the ethyl and cyanophenyl groups. The final product is purified through crystallisation or distillation.
Mechanism of action
Acetylcholinesterase (AchE) inhibitor
Description
Cyclophilin-G Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 195 amino acids (1-175 a.a.) and having a molecular mass of 21.6 kDa. Cyclophilin-G is fused to a 20 amino acid His Tag at N-terminus and is purified by proprietary chromatographic techniques.
Background
Cyclophilin-G is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and speeds up the protein folding. PPIG catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and is involved in the folding, transport, and assembly of proteins. PPIG is localized to the nuclear speckles, a nuclear compartment rich in splicing factors, and cooperates with the splicing factors SC35 and pinin. Cyclophilin-G also takes part in the regulation of pre-mRNA splicing.
Pesticide Type
Insecticide; Veterinary substance
