Synthesis
The target compound (S)-3-MORPHOLINECARBOXYLIC ACID HCL was prepared from oxolysine as the starting material via a cyclization reaction, or from morpholine as the starting material, after preparing an aldehyde-substituted morpholine, followed by an oxidation reaction to obtain (S)-3-MORPHOLINECARBOXYLIC ACID HCL. The synthetic reaction formula is shown in the figure below:

Uses
Morpholine compounds are widely found in natural products, possess strong biological activity, and serve as pharmacophores for many drugs. (S)-3-morpholinoic acid is a carboxylic acid compound that can be used as an important pharmaceutical and chemical intermediate.