Uses
Dihydrexidine is a moderately selective full agonist at the dopamine D1 and D5 receptors (1,2). It has been shown to have antiparkinson effects. It also has the ability to improving the cognitive and working memory deficits in schizophrenia and schizotypal disorder.
Biological Activity
A potent, full efficacy dopamine D 1 agonist which shows no agonist activity at peripheral D 2 receptors or adrenoceptors at doses which cause maximal stimulation of D 1 sites. The compound appears to be fully bioavailable in brain and exhibits profound antiparkinsonism effects in vivo .
