Uses
11BETA-hydroxytestosterone may be used as a drug in human or animal subjects for the prevention or reversal of mitochondrial damage, for the treatment or prevention of diseases related to mitochondrial dysfunction or depletion, and for inducing mitochondrial regeneration or remodeling as a means of treating diseases related to mitochondrial structural and functional abnormalities.
Description
11β-hydroxy Testosterone is a metabolite of testosterone.1 It is formed from testosterone primarily by the cytochrome P450 (CYP) isoform CYP3A4.WARNING This product is not for human or veterinary use.
Definition
ChEBI: 11beta-hydroxytestosterone is an androstanoid that is testosterone carrying an additional hydroxy substituent at the 11beta-position. It has a role as a bacterial xenobiotic metabolite, a human xenobiotic metabolite and a marine metabolite. It is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, an androstanoid, a C19-steroid and an 11beta-hydroxy steroid. It is functionally related to a testosterone.
References
[1] MAN HO CHOI. Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450.[J]. Drug Metabolism and Disposition, 2005, 33 6: 714-718. DOI:
10.1124/dmd.104.003327
