Description
A novel and effective difluorocarbene reagent for O-, S-, N-, C-difluoromethylation under mild
conditions. When only 1.2 equivalent of the reagent is used, the difluoromethylated products can
be obtained in moderate to excellent yields at low temperatures.
Reactions
O-, S-, N-, C-difluoromethylation
References
[1] FEI WANG Jinbo H Weizhou Huang. Difluoromethylation of O-, S-, N-, C-Nucleophiles Using Difluoromethyltri(n-butyl)ammonium Chloride as a New Difluorocarbene Source[J]. Chinese Journal of Chemistry, 2011, 29 12: 2717-2721. DOI:
10.1002/cjoc.201100325.
