Chemical Properties
Red Solid
Uses
Fluorimetric substrate. Dealkylation of pentoxyresorufin: A rapid sensitive assay for measuring induction of cytochrome(s) P-450.
Uses
A fluorescent indicator of Cytochrome P 450 activity.
Uses
Resorufin pentyl ether has been used as a substrate to study the effects of
Kaempferia parviflora extract on mouse hepatic cytochrome P450 enzymes.
General Description
Resorufin pentyl ether is an analog of resazurin. Resorufin is a redox probe which is colorless and non-fluorescent in its reduced state. On oxidation, it fluoresces red. Resorufin is used widely as an indicator in microbiological media. It can be used to differentiate between actively metabolizing cells and inactive or dead cells.
Biochem/physiol Actions
Fluorimetric substrate for cytochrome P450 linked enzymes, CYP2B and CYP2B4.