TOMEGLOVIR
- Product NameTOMEGLOVIR
- CAS233254-24-5
- CBNumberCB62451318
- MFC23H27N3O4S
- MW441.54
- MDL NumberMFCD09837851
- MOL File233254-24-5.mol
Chemical Properties
| Density | 1.334±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 108 mg/mL (244.60 mM) |
| pka | 8.96±0.50(Predicted) |
| FDA UNII | 0YPQ44B589 |
TOMEGLOVIR Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0027853 | 5mg | $110 | Tomeglovir 99.45% |
Buy |
| ChemScene CS-0027853 | 10mg | $150 | Tomeglovir 99.45% |
Buy |
| ChemScene CS-0027853 | 25mg | $300 | Tomeglovir 99.45% |
Buy |
| ChemScene CS-0027853 | 50mg | $480 | Tomeglovir 99.45% |
Buy |
| American Custom Chemicals Corporation API0019436 | 5MG | $500.25 | TOMEGLOVIR 95.00% |
Buy |
TOMEGLOVIR Chemical Properties,Usage,Production
Biological Activity
Tomeglovir is an anti-CMV agent that inhibits the progression of viral DNA concatemers with IC50 values of 0.34 μM and 0.039 μM for HCMV and MCMV, respectively.in vitro
Tomeglovir (BAY 38-4766) is a potent anti-CMV agent, with IC 50 s of 0.34 μM and 0.039 μM for HCMV and MCMV. Tomeglovir also suppresses HELF and NIH 3T3 cells, with CC 50 s of 85 μM and 62.5 μM, respectively. Tomeglovir (BAY 38-4766) inhibits HCMV Davis and various monkey CMV strains with EC 50 s of 1.03 ± 0.57 μM and < 1 μM.
in vivo
Tomeglovir (BAY 38-4766; 3, 10, 30, 100 mg/kg, po) dose-dependently reduces MCMV-DNA in salivary glands, livers and kidneys of MCMV-infected NOD-SCID mice, and prolongs the survival of the mice. It (10, 25 and 50 mg/kg) shows antiviral activity in the hollow fiber mouse model. Tomeglovir (BAY 38-4766) shows antiviral activity in SCID mice with MCMV, and the LD 50 is >2000 mg/kg in mice and rats.
target
IC50: 0.34 μM (HCMV), 0.039 μM (MCMV)
Preparation Products And Raw materials
TOMEGLOVIR Supplier
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 0510-86103381 | sales@rejoyschem.com | CHINA | 976 | 58 | |
| +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 | |
| +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 | |
| +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 | |
| 571-89925085 | sales@amadischem.com | China | 131981 | 58 | |
| sales@boylechem.com | China | 2923 | 55 | ||
| Mobile:13665161512 | China | 1785 | 58 | ||
| 025-58849295 18951903616; |
info@adooq.cn | China | 2989 | 60 | |
| 021-54581719 13817873692 |
mkt@boynerspharm.com | China | 1725 | 55 | |
| 16314854226 | info@bocsci.com | United States | 9926 | 65 |
233254-24-5, TOMEGLOVIRRelated Search
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