AMMONIUM CHLORIDE-15N

Chemical Properties

White crystalline

Uses

Ammonium-15N chloride has been used:

• as a medium supplement for the incorporation of 15N in sporulation protein, CsfB, for NMR spectroscopy
• in assaying nitrogen loss in marine sediment
• for the incorporation of 15N in apolipoprotein A-I for mass spectrum analysis

Uses

As isotope labelled analogue of Ammonium Chloride, Ammonium chloride-15N can be used in flavouring agents and nitrogen source in fertilizers.

Biochem/physiol Actions

Ammonium chloride is a component of the nitrogen cycle. Excess of ammonium chloride depletes ATP in astrocytes. Ammonium chloride inhibits the acidification in endosome-lysosome system. It is a hemolysing agent used in the lysis of erythrocytes. Ammonium chloride administration promotes creatinine and urea clearance in rat.