Description
Choline salicylate is absorbed more
rapidly than aspirin and produces higher salicylate plasma levels. It is available as a mint-flavored liquid.
Originator
Arthropan ,Purdue , US,1959
Uses
Choline Salicylate displays protective effects in the treatment of Alzheimer’s disease. It has the potential to relieve pain associated with mouth ulcers.
Definition
ChEBI: Choline salicylate is a hydroxybenzoic acid. It is functionally related to a salicylic acid.
Manufacturing Process
A method of preparation is to react an acid salt of choline (such as choline
chloride or choline bromide) with an alkaline salt of salicylic acid (such as
sodium salicylate, potassium salicylate, or magnesium salicylate) in an
alcoholic media.
brand name
Arthropan
(Purdue Frederick).
Therapeutic Function
Analgesic; Antipyretic
Clinical Use
Choline salicylate has a lower incidence of GI side effects compared with aspirin, and it has been shown to be
particularly useful in treating juvenile rheumatoid arthritis, in which aspirin was ineffective.
