cis-13,16,19-Docosatrienoic acid methyl ester

Description

Docosatrienoic acid methyl ester is an ester version of docosatrienoic acid , a rare ω-3 fatty acid not readily detected in normal phospholipid polyunsaturated fatty acid pools that inhibits [³H]-LTB₄ binding to pig neutrophils at a concentration of 5 μM. Docosatrienoic acid methyl ester is more lipid soluble than the free acid and may be more desirable than the free acid in certain formulations.

Uses

cis-13,16,19-Docosatrienoic acid methyl ester is an ester form of docosatrienoic acid, a rare omega-3 fatty acid not found in the normal phospholipid polyunsaturated fatty acid pool Easily detectable, it inhibits the binding of [3H]-LTB4 to porcine neutrophils at a concentration of 5 μM. Methyl docosatrienoate is more fat-soluble than the free acid and may be more desirable than the free acid in some formulations.

References

[1] K.A. YAGALOFF. Essential fatty acids are antagonists of the leukotriene B4 receptor[J]. Prostaglandins, leukotrienes, and essential fatty acids, 1995, 52 5: Pages 293-297. DOI: 10.1016/0952-3278(95)90029-2