Chemical Properties
Soluble in methanol, ethanol, DMSO and other organic solvents, derived from customs clearance vine.
Uses
Tenacissoside G is a C21 steroid from the stems of Marsdenia tenacissima. Tenacissoside G reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells[1][2].
Biological Activity
Tenacissoside G is a C21 steroid derived from the stem of Marsdenia tenacissima. It reverses multidrug resistance in P-glycoprotein (Pgp)-overexpressing multidrug-resistant cancer cells.
References
[1] Lei YS, et al. [C21 steroids from the stems of Marsdenia tenacissima]. Yao Xue Xue Bao. 2008 May;43(5):509-12. PMID:18717339
[2] Hu YJ, et al. Tenacigenin B derivatives reverse P-glycoprotein-mediated multidrug resistance inHepG2/Dox cells. J Nat Prod. 2008 Jun;71(6):1049-51. DOI:
10.1021/np070458f
