Description
3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(methyl orthoacetate) is a synthetic intermediate used in glycosylation reactions. Typically, the methyl orthoester protecting group is first removed by mild acid hydrolysis, producing a glycosyl donor. Removal of the O-benzyl protecting groups is performed late in the synthesis.
Chemical Properties
White Solid
Uses
3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(Methyl Orthoacetate) (cas# 16697-49-7) is a compound useful in organic synthesis.
References
[1] JOSé R. MARINO-ALBERNAS. Synthesis and Growth Inhibitory Properties of Glycosides of 1-O-Hexadecyl-2-O-methyl-sn-glycerol, Analogs of the Antitumor Ether Lipid ET-18-OCH3 (Edelfosine)[J]. Journal of Medicinal Chemistry, 1996, 39 17: 3241-3247. DOI:
10.1021/jm960164j[2] NILANJANA CHAKRABORTY Marc d’Alarcao. An anionic inositol phosphate glycan pseudotetrasaccharide exhibits high insulin-mimetic activity in rat adipocytes[J]. Bioorganic & Medicinal Chemistry, 2005, 13 24: Pages 6732-6741. DOI:
10.1016/j.bmc.2005.07.020
