ANTI-MBD2A,B (RA-18)

Uses

Anti-MBD2a,b (RA-18) antibody produced in rabbit has been used:

• for chromatin immunoprecipitation and western blotting
• immunofluorescence
• immunoblotting

Biological Activity

MBD2 binds to methylated DNA in vitro or in vivo, suggesting th at MBD2 targets the MeCP1 complex to methylated DNA. MBD2a interacts with RNA Helicase A (RHA). MBD2 protein appear to protect against some cancers.', 'Methyl-CpG binding domain protein 2 (MBD2a) acts as a repressor during transcription.