Description
Cilazapril is a new ACE inhibitor useful in the management of mild to moderate
hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its
active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is
more potent and longer lasting.
Chemical Properties
White or almost white, crystalline powder.
Originator
Hoffmann-LaRoche (Switzerland)
Definition
ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.
brand name
Inhibace (Hoffmann-LaRoche).
