TRICHODESMINE

Description

The structure of this pyrrolizidine alkaloid has recently been shown to be that given above which has been elucidated from chemical and spectroscopic data.

Uses

Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south eastern desert of Egypt. Trichodesmine is also known to have toxic effects on pyrrole binding and Glutathione (G597951) metabolism in the rat.

References

Rashkes, Abdullaev, Yunusov, Khim. Prir. Soedin., 10,40 (1974)