GTP TRIS SALT

Uses

GTP from Sigma was used

• in a study to induce dissociation of the endogenous neuropeptide galanin from its binding sites prior to incubation with radiolabeled ligand
• as a substrate along with FtsZ in a colorimetric assay to detect GTPase activity to test polymerization of FtsZ, the prokaryotic ortholog of tubulin, in the absence of Na⁺
• as a pipette solution for patch-clamp Ca²⁺ measurements in a study
• as an internal standard during the analysis of water-soluble inositol phosphate

General Description

Guanosine 5′-triphosphate (GTP) is a molecule rich in energy.

Biochem/physiol Actions

The extracellular guanosine 5′-triphosphate (GTP) acts as an enhancer of myogenic cell differentiation. It plays a key role in miRNA-myogenic regulator factor modulation. It also participates in the release of exosome stuffed with guanosine and guanosine-based molecules secretion. GTP is considered as an activated precursor forRNA synthesis. It also plays a major role in the synthesis and localization of protein,signal transduction, visualexcitation and hormone action.