Description
(±)5(6)-
EpETE methyl ester is a derivative of 5(6)-
EpETE which is stable enough to ship and handle routinely.(±) 5(6)-
EpETE methyl ester is a chemically less reactive derivative of 5(6)-
EpETE. The active free acid can be generated from the methyl ester by careful base hydrolysis. Epoxy eicosatetraenoic acids (EpETEs) are the epoxygenase metabolites of EPA. A number of vicinal diol metabolites of EpETEs have been detected in the plasma of patients on marine oil dietary supplementation, while in subjects on a typical western diet these compounds are generally not detected.
1 The specific biologic activity of 5(6)-
EpETE and its methyl ester have not been documented.
References
1. Knapp, H.R., Miller, A.J., and Lawson, J.A.
Urinary excretion of diols derived from eicosapentaenoic acid during N-3 fatty acid ingestion Prostaglandins 42,47-53(1991).
