Description
This alkaloid possesses a similar structure to that of Nerinine (q.v.) and is found
in Nerine krigeii. It may be crystallized from AcOEt and is dextrorotatory with
[0:]54 + 161.6° (c 0.57, CHC13). It is hygroscopic and behaves as a monoacidic
base yielding a picrate as yellow prisms, m.p. 205-9°C (dec.); a methiodide, m.p.
260-5°C (dec.) and a crystalline O-acetate, m.p. 20t-2°C. It contains a lactone
ring which may be opened by alkalies and regenerated by acids.
References
Briggs et at., J. Arner. Chern. Soc., 78,2899 (1956)
Jeffs, Hawksworth., Tetrahedron Lett., 217 (1963)
