Uses
Dichlorotitanium diisopropoxide is a Lewis acid frequently used in the preparation of chiral titanium complexes; an efficient catalyst for Diels-Alder reactions, [2 + 2] cycloadditions, and carbonyl-ene reactions, including asymmetric versions of these processes; a reagent for titanium enolate formation; and a catalyst component for the stereoselective addition of cyanide and allyltin nucleophiles to aldehydes.
Preparation
Dichlorotitanium diisopropoxide is prepared by adding slowly at rt an equimolar amount of Titanium(IV) Chloride to a hexane solution of Titanium Tetraisopropoxide; following mixing, during which heat is evolved, the mixture is allowed to stand at rt for 6 h and the precipitate is collected and washed with hexane; dibromotitanium diisopropoxide is prepared similarly.
storage
Corrosive; moisture sensitive; use in a fume hood; can be stored under nitrogen in pure form or in solution.
