(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 3,4-dimethoxybenzoate

Uses

Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC50 = 289 nM), exhibiting cognitive and neuroprotective properties[1][2].

Definition

ChEBI: Convolamine is a methoxybenzoic acid.

References

[1] Gapparov A M, et al. Alkaloids of Convolvulus subhirsutus from Uzbekistan[J]. Chemistry of Natural Compounds, 2007, 43: 291-292.
[2] Crouzier L, et al. Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma‐1 receptor‐positive modulator with cognitive and neuroprotective properties[J]. Phytotherapy Research, 2024, 38(2): 694-712.