Chemical Properties
White powder
Uses
Phe-Arg -naphthylamide dihydrochloride has been used to evaluate the contribution of efflux pumps to antimicrobial resistance. It has also been used for minimal inhibitory concentration testing in the presence of an efflux pump inhibitor.
Uses
Phe-Arg-beta-naphthylamide Dihydrochloride can be used as a reagent in organic synthesis.
Uses
Substrate for dipeptidyl aminopeptidase I (cathepsin C).
General Description
Phe-Arg β-naphthylamide, a peptidomimetic compound, is an efflux pump inhibitor (EPI). It acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. Phe-Arg -naphthylamide lowers fluoroquinolone resistance in
Pseudomonas aeruginosa.
