13-Deoxocarminomycin

Uses

13-Deoxycarminomycin is used as antitumor agents in preparation of 3''-Deamino-3''-(2"-pyrroline-1"-yl)-5-imine-13-deoxyanthracyclines. 13-Deoxycarminomycin is a doxA gene confers on the transformed host the ability to convert Daunomycin and 13-Dihydrodaunomycin to Doxorubicin.

Definition

ChEBI: 13-deoxycarminomycin is a cytotoxic anthracycline antibiotic that is produced by Streptomyces peucetius var. carminatus (a biochemical mutant of Streptomyces peucetius var. caesius), and is active against P-388 murine leukemia. It has a role as an antineoplastic agent and a bacterial metabolite. It is an anthracycline antibiotic, an aminoglycoside antibiotic, a member of p-quinones, a member of tetracenequinones and a tertiary alcohol. It is a conjugate base of a 13-deoxycarminomycin(1+). It derives from a hydride of a tetracene.