alpha-Hydroxybenzenepropanoic acid methyl ester

Chemical Properties

Uses

• As an intermediate in the synthesis of bortezomib analogs as 20S proteasome inhibitors.
• As a substrate in the amination of the benzylic C-H bonds and the aminated products are further used to prepare β-lactams.
• As an intermediate in one of the key synthetic steps for the preparation of YM-254890 analog, a selective Gαq/11 inhibitor.