Synthesis
First, iodine is used as the initiator to synthesize the Grignard reagent n-pentylmagnesium bromide using magnesium powder. This operation must be performed under strictly anhydrous conditions. Then, it is reacted with 3,4-dihydro-2H-pyran to synthesize 4-penten-1-ol, which is difficult to synthesize by other methods. The synthesis reaction is shown in the figure below:
Figure 4-penten-1-ol synthesis reaction diagram
Chemical Properties
4-Penten-1-ol is Colourless Liquid
Uses
4-Penten-1-ol is a reagent used in carbohydrate chemistry for n-Pentenyl Glycoside methodology for the rapid assembly of homoglycans exemplified with the nonasaccharide component of a high-mannose glycoprotein.
Uses
4-Penten-1-ol is used as a reagent used in carbohydrate chemistry for n-Pentenyl Glycoside methodology in the rapid assembly of homoglycans exemplified with the nonasaccharide component of a high-mannose glycoprotein. It can be used in agrochemical, pharmaceutical and dyestuff field etc. 4-Penten-1-ol is used to study the epoxidation of olefins with oxo-diperoxo tungstate(VI) complex as catalyst and bicarbonate as co-catalyst.
General Description
4-penten-1-ol forms ester bond at the C terminus of the linear peptide in solution with HATU as coupling agent.
Safety Profile
Dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes.
