Uses
Globulins Cohn fraction IV-4 human has been used in differential scanning calorimetry (DSC) to test the effect of low-dose ionizing radiation. It has also been used in the preparation of plasma protein solution for biophysical studies.
Definition
Substance separated from citrated bovine plasma.
General Description
Cohn fraction IV consists of α and β-globulins. It is a plasma by-product produced during γ-globulin synthesis.
Biochem/physiol Actions
The Cohn fraction IV (α-globin enriched) mediates the inhibition of brain neurotransmitter receptors.