2-[(1-OXO-9Z-OCTADECENYL)AMINO]-ETHANESULFONIC ACID

Description

Several different arachidonoyl amino acids, including N-arachidonoyl dopamine and N-arachidonoyl serine, have been isolated and characterized from bovine brain. During mass spectral lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, were discovered. This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels. N-Oleoyl taurine is an amino-acyl endocannabinoid isolated from rat brain that may activate TRPV1 and TRPV4.

Uses

N-Oleoyl Taurine which belongs to the class of N-Acyl Taurines were detected in beta cells of Langerhans islets causing insulin secretion results beta cell dysfunction in type 2 diabetes

Definition

ChEBI: N-oleoyltaurine is a fatty acid-taurine conjugate derived from oleic acid. It has a role as a human blood serum metabolite, an apoptosis inducer and an antineoplastic agent. It is functionally related to an oleic acid. It is a conjugate acid of a N-oleoyltaurine(1-).