EMA400
- Product NameEMA400
- CAS152362-51-1
- CBNumberCB33345282
- MFC32H29NO5
- MW507.58
- MOL File152362-51-1.mol
Chemical Properties
| Boiling point | 745.3±60.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| pka | 3.54±0.20(Predicted) |
EMA400 Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Biosynth CGA36251 | 1mg | $250 | 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid |
Buy |
| Biosynth CGA36251 | 5mg | $464.05 | 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid |
Buy |
| Biosynth CGA36251 | 10mg | $742.5 | 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid |
Buy |
| Biosynth CGA36251 | 25mg | $1392 | 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid |
Buy |
| Biosynth CGA36251 | 50mg | $2227 | 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid |
Buy |
EMA400 Chemical Properties,Usage,Production
Uses
rac-Olodanrigan (rac-EMA401; EMA400) is a racemic mixture of the S-enantiomer (EMA401; HY-13106) and R-enantiomer (EMA402). rac-Olodanrigan is a potent and selective AT2 receptor antagonist with IC50s of 75.2 nM and 2918 nM for AT2R and AT1R, respectively. rac-Olodanrigan evokes dose-dependent relief of mechanical allodynia in the ipsilateral hind paws of rats with a chronic constriction injury (CCI) of the sciatic nerve[1].IC 50
AT2 Receptor: 75.2 nM (IC50); AT1 Receptor: 2918 nM (IC50)References
[1] Maree T Smith. Nonopioid analgesics discovery and the Valley of Death: EMA401 from concept to clinical trial. Pain. 2022 Nov 1;163(Suppl 1):S15-S28. DOI:10.1097/j.pain.0000000000002675Preparation Products And Raw materials
EMA400 Supplier
Global(17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 7996 | 62 | |
| 13917420128 13062833949 |
fred.wen@crcorporation.cn | China | 9778 | 58 | |
| 021-58111628 15800915896 |
sales@twochem.com | China | 1782 | 58 | |
| 021-000000 | admin@jingshipharmatech.com | China | 9942 | 58 | |
| 0595-22008920; 18120708884 |
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sales@pharm-intermediates.com | China | 1976 | 58 | |
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| fred.wen@crcorporation.cn | China | 8642 | 58 | ||
| +86-0371-86658258 +86-13203830695 |
laboratory@coreychem.com | China | 30203 | 58 | |
| 15021845385 | 765325601@qq.com | China | 3607 | 58 |
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