Chemical Properties
2-Mercaptopyridine is yellow crystalline powder
Uses
Employed as a ligand in metal complexes. It can be used to coat porous media to purify plasmid DNA.
Uses
Employed as a ligand in metal complexes.1,2
Uses
2-Mercaptopyridine Can be used to coat porous media to purify plasmid DNA.
Definition
ChEBI: Pyridine-2-thiol is pyridine substituted at C-2 by a sulfanyl group. It has a role as a fluorescence quencher and an allergen. It is a member of pyridines and an aryl thiol.
Purification Methods
If impure, dissolve in CHCl3, wash with dilute AcOH, H2O, dry (MgSO4), evaporate under reduced pressure and recrystallise the residue from *C6H6 or H2O. 2-Methylmercaptopyridine (b 100-104o/33mm, pK2 0 3.59) was formed by treatment with MeI/NaOH. [Albert & Barlin J Chem Soc 2394 1959, Phillips & Shapiro J Chem Soc 584 1942, Beilstein 21 H 45, 21 III/IV 373, 21/7 V 147.]
