Chemical Properties
Pink to beige crystalline powder
Chemical Properties
4-Hydroxybenzyl alcohol is a white crystalline powder with slightly fruity-sweet coconut odor
Occurrence
Reportedly found in vanilla, Bourbon (Vanilla plantifolia Andrew
Uses
4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Definition
ChEBI: P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols.
Preparation
Prepared from p-cresol by using the microorganism, Pseudomonas putida.
General Description
4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in
Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.
Flammability and Explosibility
Not classified
Contact allergens
Methylol phenols are sensitizers contained in resins
based on phenol and formaldehyde of the resol type.
Cross-reactivity is possible with other phenol derivative
molecules.
IC 50
IC50 >0.2 mM (human); ALDH5A1: IC50 >1 mM (human); ABAT: IC50 >1 mM (human); Tyrosinase: IC50 >1 mM (Agaricus bisporus)
Purification Methods
Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]
